Many wastes are biodegradable, that is, they can be broken down and used as food by microorganisms like bacteria. We tend to think of biodegradable wastes as being preferable to non-biodegradable ones, because they will be broken down and not remain in the environment for very long times. Too much biodegradable material, though, can cause the serious problem of oxygen depletion in receiving waters.

Like fish, aerobic bacteria that live in water use oxygen gas which is dissolved in the water when they consume their "food". (The oxygen in the compound H₂O, water, is chemically bound, and is not available for respiration (breathing)). But, oxygen is not very soluble in water. Even when the water is saturated with dissolved oxygen, it contains only about 1/25 the concentration that is present in air. So if there is too much "food" in the water, the bacteria that are consuming it can easily use up all of the dissolved oxygen, leaving none for the fish, which will die of suffocation.

Once the oxygen is gone (depleted), other bacteria that do not need dissolved oxygen take over. But while aerobic microorganisms-- those which use dissolved oxygen-- convert the nitrogen, sulfur, and carbon compounds that are present in the wastewater into odorless-- and relatively harmless-- oxygenated forms like nitrates, sulfates and carbonates, these anaerobic microorganisms produce toxic and smelly ammonia, amines, and sulfides, and flammable methane (swamp gas). Add in the dead fish, and you see why we don't want large amounts of biodegradable materials entering lakes and streams.